KMID : 0390220130240010066
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Journal of Clinical Otolaryngology, Head and Neck Surgery 2013 Volume.24 No. 1 p.66 ~ p.72
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Analysis of Prognostic Risk Factors of Parotid Cancer
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Kwon Hyun-Keun
Kim Sung-Dong Park Young-min Lee Won-Yong Lim Yun-Sung Lee Jin-Choon Wang Soo-Geun Lee Byung-Joo
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Abstract
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Background and Objectives£ºCancer developing in the parotid gland tends to be large variety of histologic types. The relative rarity of parotid cancer makes epidemiologic study more difficult. To develop a rational therapeutic plan for parotid cancer, the surgeon must be fully cognizant of the factors that may affect survival. The objective of this study was to identify the clinical feature and prognostic factors of parotid cancer.
Materials and Methods£ºThe authors retrospectively studied 72 patients with histologically confirmed parotid cancer at Pusan National University Hospital between 1995 and 2011. We analyzed 5-year survival rate according to the some prognostic factors.
Results£ºThe overall 5-year survival rate was 82.5%. We observed statistically significant differences for patients of different clinical stages (p=0.009), regional lymph node metastasis (p£¼0.001), preoperative facial nerve involvement (p=0.001), distant metastasis (p£¼0.001). There was no statistically significant difference in the tumor size, surgical margin, histologic grade. Superficial parotidectomy may be a safe procedure without potential morbidity, such as postoperative facial palsy.
Conclusions£ºClinical stages, regional lymph node metastasis, preoperative facial nerve involvement and distant metastasis are the significant prognostic factors, and these factors need to be considered in the treatment of parotid cancer.
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KEYWORD
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Parotid cancer, Survival, Prognosis
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